MEDIPOST announced that 3 year long term tracking clinical trial after ‘CARTISTEM®’ injection was implemented, and the result proved safety with superior treatment effect vis-à-vis reference groups.
MEDIPOST implemented long term tracking clinical trial on the third phase clinical trial subjects for CARTISTEM®’ injection and reference groups, at 10 clinical trial centers comprising Samsung Seoul Hospital etc.
MEDIPOST explained the result that ‘CARTISTEM®’ was found as be far superior in treatment effect than reference groups in every assessment method comprising knee pain∙ function∙vitality assessment (IKDC), ostanthritis symptom assessment (WOMAC), pain index assessment (VAS) etc.
Firstly in IKDC assessment (increases in tandem with functionality), CARTISTEM® treatment group’s average increase was higher by 3 times vis-à-vis the average increase by reference groups, by comparison of the status at pre-treatment and after 3 years from treatment. .
Also in WOMAC assessment (decreases in tandem with improving symptom) ‘CARTISTEM®’ treatment group showed stronger improvement in ostarthritis, in with width of decrease which is more than 3 times vis-à-vis reference groups.
Also in the VAS assessment (decreases in tandem with lower pain) indicating the level of knee pain, ‘CARTISTEM®’ treatment group obtained more than statistically meaningful scores than reference groups. .
Especially, ‘CARTISTEM®’ treatment group and the reference group showed wider performance gap at the time of one year from the clinical trial than at the time of 3 phase test completion, in all assessment items, proving the superiority of ‘CARTISTEM®’ in long term treatment effect such as sustained improvement of symptom and prevention of recurrence etc.