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CARTISTEM | 2024-10-18 Implantation of hUCB-MSCs generates greater hyaline-type cartilage than microdrilling combined with high tibial osteotomy
The repaired cartilage after CARTISTEM implantation combined with HTO showed greater hyaline cartilage with rigidity than that after microdrilling in knee osteoarthritis.· Issue information | Knee Surg Sports Traumatol Arthrosc. 2024 Apr; 32(4):829-842. doi: 10.1002/ksa.12100. · Co-author | Se-Han Jung, Hyunjin Park, Min Jung, Kwangho Chung, Sungjun Kim, Hyun-Soo Moon, Jisoo Park, Ju-Hyung Lee, Chong-Hyuk Choi & Sung-Hwan Kim |
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CARTISTEM | 2024-02-09 Allogeneic umbilical cord blood‑derived mesenchymal stem cell implantation versus microdrilling combined with high tibial osteotomy for cartilage regeneration
CARTISTEM implantation combined with HTO was more effective than microdrilling for patient-reported outcomes and cartilage regeneration in knee osteoarthritis.· Issue information | Sci Rep. 2024 Feb 9;14(1):3333. doi: 10.1038/s41598-024-53598-9. · Co-author | Se‑Han Jung, Bum‑Joon Nam, Chong‑Hyuk Choi, Sungjun Kim, Min Jung, Kwangho Chung, Jisoo Park, Youngsu Jung & Sung‑Hwan Kim |
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CARTISTEM | 2023-07-17 Dry Arthroscopic Cartilage Repair of the Knee Joint Using Umbilical Cord Mesenchymal Stem Cells: Kelly Clamp Technique
Arthroscopic CARTISTEM implantation using a Kelly clamp is an easier and more effective method.· Issue information | Arthrosc Tech. 2023 Jul 17;12(8):e1355-e1359. doi: 10.1016/j.eats.2023.04.004. · Co-author | Tae Jin Lee, Chan Dong Jeong, Tae Hoon Lee |
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CARTISTEM | 2023-04-24 Clinical and Magnetic Resonance Imaging Outcomes After Human Cord Blood–Derived Mesenchymal Stem Cell Implantation for Chondral Defects of the Knee
Clinical outcomes improved significantly at short-term follow-up after CARTISTEM implantation for chondral defects of the knee.· Issue information | Orthop J Sports Med. 2023 Apr 24;11(4):23259671231158391. doi: 10.1177/23259671231158391. · Co-author | Jun-Seob Song, Ki-Taek Hong, Na-Min Kim, Byung-Hun Hwangbo, Bong-Seok Yang, Brian N. Victoroff, and Nam-Hong Choi |
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CARTISTEM | 2023-03-22 Bone Marrow Aspirate Concentrate versus Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells for Combined Cartilage Regeneration Procedure in Patients Undergoing High Tibial Osteotomy: A Systematic Review and Meta-Analysis
Both BMAC and CARTISTEM with HTO improved clinical outcomes in varus knee OA patients, but CARTISTEM were more effective in articular cartilage regeneration than BMAC augmentation.· Issue information | Medicina (Kaunas). 2023 Mar 22;59(3):634.doi: 10.3390/medicina59030634. · Co-author | Dojoon Park, Youn Ho Choi, Se Hyun Kang, Hae Seok Koh, Yong In |
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CARTISTEM | 2023-03-14 Safety and effectiveness of arthroscopic-assisted implantation of allogenic umbilical cord blood-derived mesenchymal stem cells
For individuals with Osteoarthritis of the knee, chondroplasty with CARTISTEM during medial owHTO can significantly improve the radiological and clinical outcomes.· Issue information | Arthroscopy and Orthopedic Sports Medicine 10(1):28-33.doi: 10.14517/aosm23001. · Co-author | Dong Hyuk Cha, Dong Hwi Kim, Jeong Min Kook |
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CARTISTEM | 2023-01-11 Allogeneic Umbilical Cord-Blood-Derived Mesenchymal Stem Cells and Hyaluronate Composite Combined with High Tibial Osteotomy for Medial Knee Osteoarthritis with Full-Thickness Cartilage Defects
CARTISTEM-HA composite implantation combined with HTO would be a good therapeutic option for patients with knee OA and full-thickness cartilage defects.· Issue information | Medicina (Kaunas). 2023 Jan 11;59(1):148. doi: 10.3390/medicina59010148. · Co-author | Yong-Beom Park, Han-Jun Lee, Hyun-Cheul Nam and Jung-Gwan Park |
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CARTISTEM | 2022-12-06 Repair of a large patellar cartilage defect using human umbilical cord blood-derived mesenchymal stem cells: A case report
CARTISTEM implantation may be a useful treatment option for the repair of large patellar cartilage defects.· Issue information | World J Clin Cases. 2022 Dec 6;10(34):12665-12670. doi: 10.12998/wjcc.v10.i34.12665. · Co-author | Jun-Seob Song, Ki-Taek Hong, Ki Jeon Song, Seok Jung Kim |
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CARTISTEM | 2022-09-22 Cost Effectiveness of Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Patients with Knee Osteoarthritis
CARTISTEM was cost effective compared with microfracture in patients with knee OA.· Issue information | Appl Health Econ Health Policy. 2022 Sep 22. doi: 10.1007/s40258-022-00762-9. · Co-author | Kangho Suh, Brian J Cole, Andreas Gomoll, Seung-Mi Lee, Hangseok Choi, Chul-Won Ha, Hong Chul Lim, Myung Ku Kim, Gwi-Yeom Ha, Dong-Churl Suh |
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CARTISTEM | 2022-09-09 Cartilage Regeneration in Osteoarthritic Patients by a Composite of Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cells and Hyaluronate Hydrogel: Results from a Clinical Trial for Safety and Proof-of-Concept with 7 Years of Extended Follow-Up
In the Phase 1/2a clinical trial, CARTISTEM implantation showed safety of treatment and effective regeneration of durable articular cartilage in osteoarthritic knees with 7 years of extended follow-up.· Issue information | Stem Cells Trans Med. 2017 Feb;6(2):613-621. doi: 10.5966/sctm.2016-0157. · Co-author | Yong-Beom Park, Chul-Won Ha, Choong-Hee Lee, Young Cheol Yoon, Yong Geun Park |