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Others | 2025-05-02 Umbilical Cord Blood Plasma Enhances Cellular Repair and Senescence Suppression in Human Dermal Fibroblasts Under Oxidative Stress
The anti-aging effects of UCBP (Umbilical cord blood plasma) extend beyond ROS reduction, potentially through modulation of the senescence-associated secretory phenotype and enhancement of tissue repair mechanisms.· Issue information | Rejuvenation Res. 2025 May 2. doi: 10.1089/rej.2024.0085. · Co-author | Miso Jeong, Hyangju Lee, Tae-Hyun Ko, Soo Jin Choi, Wonil Oh, Sangwoo Kim |
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CARTISTEM | 2025-04-28 Treatment of osteoarthritic knee with high tibial osteotomy and allogeneic human umbilical cord blood-derived mesenchymal stem cells combined with hyaluronate hydrogel composite
CARTISTEM implantation with HTO is an effective treatment for medial compartment osteoarthritis and varus deformities, resulting in significant improvements in cartilage regeneration and overall clinical outcomes.· Issue information | Stem Cell Res Ther. 2025 Apr 28, 16(1):211.doi: 10.1186/s13287-025-04356-9. · Co-author | Bo Seung Bae, Jae Woong Jung, Gyeong Ok Jo, Seon Ae Kim, Eun Jeong Go, Mi-La Cho, Asode Ananthram Shetty, Seok Jung Kim |
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CARTISTEM | 2025-04-21 Effect of preoperative medial meniscus status on the outcomes of high tibial osteotomy with human umbilical cord-derived mesenchymal stem cells cartilage regeneration
HTO with CARTISTEM implantation provided significant clinical improvements and effective cartilage regeneration regardless of preoperative medial meniscus status.· Issue information | Orthop Traumatol Surg Res. 2025 Feb 1:104179. doi: 10.1016/j.otsr.2025.104179. · Co-author | Dhong-Won Lee, Sung-Wook Hong, Seung-Ik Cho, Sung-Gyu Moon & Ji-Hee Kang. |
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CARTISTEM | 2025-04-21 Anterior to Central Cartilage Defects of Arthritic Knee Showed Better Cartilage Regeneration Than Posterior Cartilage Defects using Mesenchymal Stem Cell Implantation
Cartilage defects with osteoarthritis, which is smaller and primarily limited to the anterior to-central portion showed better MOCART scores after CARTISTEM implantation.· Issue information | Arthroscopy. 2024 Dec 2:S0749-8063(24)01013-2. doi: 10.1016/j.arthro.2024.11.083. · Co-author | Se-Han Jung, Hong Seon Lee, Min Jung, Kwangho Chung, Sungjun Kim, Jeehoon Choi, Chong-Hyuk Choi & Sung-Hwan Kim. |
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CARTISTEM | 2024-10-18 Implantation of hUCB-MSCs generates greater hyaline-type cartilage than microdrilling combined with high tibial osteotomy
The repaired cartilage after CARTISTEM implantation combined with HTO showed greater hyaline cartilage with rigidity than that after microdrilling in knee osteoarthritis.· Issue information | Knee Surg Sports Traumatol Arthrosc. 2024 Apr; 32(4):829-842. doi: 10.1002/ksa.12100. · Co-author | Se-Han Jung, Hyunjin Park, Min Jung, Kwangho Chung, Sungjun Kim, Hyun-Soo Moon, Jisoo Park, Ju-Hyung Lee, Chong-Hyuk Choi & Sung-Hwan Kim |
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CARTISTEM | 2024-02-09 Allogeneic umbilical cord blood‑derived mesenchymal stem cell implantation versus microdrilling combined with high tibial osteotomy for cartilage regeneration
CARTISTEM implantation combined with HTO was more effective than microdrilling for patient-reported outcomes and cartilage regeneration in knee osteoarthritis.· Issue information | Sci Rep. 2024 Feb 9;14(1):3333. doi: 10.1038/s41598-024-53598-9. · Co-author | Se‑Han Jung, Bum‑Joon Nam, Chong‑Hyuk Choi, Sungjun Kim, Min Jung, Kwangho Chung, Jisoo Park, Youngsu Jung & Sung‑Hwan Kim |
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CARTISTEM | 2023-07-17 Dry Arthroscopic Cartilage Repair of the Knee Joint Using Umbilical Cord Mesenchymal Stem Cells: Kelly Clamp Technique
Arthroscopic CARTISTEM implantation using a Kelly clamp is an easier and more effective method.· Issue information | Arthrosc Tech. 2023 Jul 17;12(8):e1355-e1359. doi: 10.1016/j.eats.2023.04.004. · Co-author | Tae Jin Lee, Chan Dong Jeong, Tae Hoon Lee |
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CARTISTEM | 2023-04-24 Clinical and Magnetic Resonance Imaging Outcomes After Human Cord Blood–Derived Mesenchymal Stem Cell Implantation for Chondral Defects of the Knee
Clinical outcomes improved significantly at short-term follow-up after CARTISTEM implantation for chondral defects of the knee.· Issue information | Orthop J Sports Med. 2023 Apr 24;11(4):23259671231158391. doi: 10.1177/23259671231158391. · Co-author | Jun-Seob Song, Ki-Taek Hong, Na-Min Kim, Byung-Hun Hwangbo, Bong-Seok Yang, Brian N. Victoroff, and Nam-Hong Choi |
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CARTISTEM | 2023-03-22 Bone Marrow Aspirate Concentrate versus Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells for Combined Cartilage Regeneration Procedure in Patients Undergoing High Tibial Osteotomy: A Systematic Review and Meta-Analysis
Both BMAC and CARTISTEM with HTO improved clinical outcomes in varus knee OA patients, but CARTISTEM were more effective in articular cartilage regeneration than BMAC augmentation.· Issue information | Medicina (Kaunas). 2023 Mar 22;59(3):634.doi: 10.3390/medicina59030634. · Co-author | Dojoon Park, Youn Ho Choi, Se Hyun Kang, Hae Seok Koh, Yong In |
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CARTISTEM | 2023-03-14 Safety and effectiveness of arthroscopic-assisted implantation of allogenic umbilical cord blood-derived mesenchymal stem cells
For individuals with Osteoarthritis of the knee, chondroplasty with CARTISTEM during medial owHTO can significantly improve the radiological and clinical outcomes.· Issue information | Arthroscopy and Orthopedic Sports Medicine 10(1):28-33.doi: 10.14517/aosm23001. · Co-author | Dong Hyuk Cha, Dong Hwi Kim, Jeong Min Kook |