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SMUP-Cell | 2021-01-03 Senescence-Associated Secretory Phenotype Suppression Mediated by Small-Sized Mesenchymal Stem Cells Delays Cellular Senescence through TLR2 and TLR5 Signaling.
A small cell from UCB-MSCs exhibit delayed cellular senescence by inhibiting the process of TLR signaling-mediated senescence-associated secretory phenotype (SASP) activation.· Issue information | Cells. 2021 Jan 3;10(1):63. doi: 10.3390/cells10010063. · Co-author | Ji Hye Kwon, Miyeon Kim, Soyoun Um, Hyang Ju Lee, Yun Kyung Bae, Soo Jin Choi, Hyun Ho Hwang, Wonil Oh, Hye Jin Jin |
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Stem Cells | 2020-12-26 Prospects for the therapeutic development of umbilical cord blood-derived mesenchymal stem cells.
This article reviewed the current literature pertaining to the UCB-derived MSC application as potential treatment strategies, and discuss the concerns regarding the safety and mass production issues in future applications.· Issue information | World J Stem Cells. 2020 Dec 26;12(12):1511-1528. doi: 10.4252/wjsc.v12.i12.1511. · Co-author | Soyoun Um, Jueun Ha, Soo Jin Choi, Wonil Oh, Hye Jin Jin |
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CARTISTEM | 2020-10-17 Allogeneic umbilical cord blood-derived mesenchymal stem cells combined with high tibial osteotomy: a retrospective study on safety and early results
CARTISTEM implantation combined with HTO for medial knee osteoarthritis was safe and showed cartilage status improvement.· Issue information | Int Orthop. 2021 Feb;45(2):481-488. doi: 10.1007/s00264-020-04852-y. · Co-author | Young-Woo Chung, Hong-Yeol Yang, Sung-Ju Kang, Eun-Kyoo Song, Jong-Keun Seon |
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CARTISTEM | 2020-07-27 Comparison of Bone Marrow Aspirate Concentrate and Allogenic Human Umbilical Cord Blood Derived Mesenchymal Stem Cell Implantation on Chondral Defect of Knee: Assessment of Clinical and Magnetic Resonance Imaging Outcomes at 2-Year Follow-Up
Implantation of BMAC or CARTISTEM is safe and effective for repairing cartilage lesion on Chondral Defect of Knee with 2 years follow-up.· Issue information | Cell Transplant. 2020 Jan-Dec;29:1-10. doi: 10.1177/0963689720943581. · Co-author | Dong Jin Ryu, Yoon Sang Jeon, Jun Sung Park, Gi Cheol Bae, Jeong-Seok Kim, Myung Ku Kim |
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Stem Cells | 2020-07-18 Galectin-3 Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Reduces Aberrant Tau Phosphorylation in an Alzheimer Disease Model
hUCB-MSCs-secreted GAL-3 reduces Aberrant tau phosphorylation in AD model· Issue information | Stem Cells Int. 2020 Jul 18;2020:8878412.doi:10.1155/2020/8878412 · Co-author | Hoon Lim, Dahm Lee, Wan Kyu Choi, Soo Jin Choi, Wonil Oh, Dong Hyun Kim |
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CARTISTEM | 2020-06-26 High tibial osteotomy with human umbilical cord blood-derived mesenchymal stem cells implantation for knee cartilage regeneration
Implantation of CARTISTEM with concomitant HTO is an effective treatment for improving cartilage regeneration in patients with medial compartment osteoarthritis and varus deformity.· Issue information | World J Stem Cells. 2020 Jun 26;12(6):514-526. doi: 10.4252/wjsc.v12.i6.514. · Co-author | Jun-Seob Song, Ki-Taek Hong, Chae-Gwan Kong, Na-Min Kim, Jae-Yub Jung, Han-Soo Park, Young Ju Kim, Ki Bong Chang, Seok Jung Kim |
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Others | 2020-05-28 Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth
Application of conditioned medium (CM) from human umbilical cord blood-derived MSCs (hUCB-MSCs) improved hair growth and developed a method to reliably produce this optimized CM· Issue information | Cells, 2020 May 28;9(6):1344. doi: 10.3390/cells9061344. · Co-author | Hyun Ah Oh, Jihye Kwak, Beom Joon Kim, Hye Jin Jin, Won Seok Park, Soo Jin Choi, Wonil Oh, Soyoun Um |
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SMUP-Cell | 2020-04-28 A Small-Sized Population of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Shows High Stemness Properties and Therapeutic Benefit
A small-sized population of human UCB-MSC improved therapeutic effects in an elastase-induced emphysema model.· Issue information | Stem Cells Int. 2020 Apr 28;2020:5924983. doi: 10.1155/2020/5924983. · Co-author | Miyeon Kim, Yun Kyung Bae, Soyoun Um, Ji Hye Kwon, Gee-Hye Kim, Soo Jin Choi, Wonil Oh, Hye Jin Jin |
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Stem Cells | 2020-04-17 Primary cilia mediate Wnt5a/β-catenin signaling to regulate adipogenic differentiation of human umbilical cord blood-derived mesenchymal stem cells following calcium induction
Ciliogenesis was negatively regulated by Wnt5a/β-catenin signaling during adipogenesis.· Issue information | Tissue Eng Regen Med. 2020 Apr;17(2):193-202. doi: 10.1007/s13770-019-00237-4. · Co-author | Yun Kyung Bae, Gee-Hye Kim, Ji Hye Kwon, Miyeon Kim, Soo Jin Choi, Wonil Oh, Soyoun Um, Hye Jin Jin |
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CARTISTEM | 2020-01-24 Human umbilical cord blood-derived mesenchymal stem cell implantation for osteoarthritis of the knee
CARTISTEM implantation regenerated cartilage and showed satisfactory clinical outcomes in patients older than 60 years who had Medial Compartment Osteoarthritis of Knee.· Issue information | Arch Orthop Trauma Surg. 2020 Apr;140(4):503-509. doi: 10.1007/s00402-020-03349-y. · Co-author | Jun-Seob Song, Ki-Taek Hong, Na-Min Kim, Han-Soo Park , Nam-Hong Choi |